The current investigation deals with the study of phytochemical screening, antioxidant, and anti-inflammatory activities of Pelatantheria insectifera, an endangered epiphytic orchid species. Four different fractions i.e. Metahnol, n-Hexane, Butanol, and Dichloromethane (DCM) of the leaf, stem, and root of P. insectifera were considered for bioactivity test following standard protocol. The qualitative test for alkaloid and ten other secondary metabolites of this orchid showed positive results for alkaloids, tannins, flavonoids, steroids, coumarins, and terpenoids. Antioxidant activity of the Butanol-1 fraction of leaf showed the highest scavenging activity of 98.95% at concentration 250 μgml-1 compared with the highest scavenging activity of Ascorbic acid (99.69% at concentration 250 μgml-1). On the other hand, the antiinflammatory activity of P. insectifera was evaluated using heat-induced albumin denaturation assay and the experiment revealed that the DCM fraction of root showed the highest inhibition measuring 73.50%, whereas Aspirin, a standard anti-inflammatory drug showed 52.12% inhibition against egg albumin denaturation. These results indicate that orchid species may prove as a promising source of bioactive agents which can be used for treating several kinds of ailments related with inflammatory complexity.