Journal

Antioxidant and anti-inflammatory potential of Dendrobium moschatum fractions of root, stem, and leaf was investigated. The dried samples of these parts were extracted with Butanol-1, DCM (dichloromethane), n-Hexane, and Methanol fractions. Both Methanol fraction of root [IC50 (inhibition concentration 50 µgml ) = 30.21 µgml ] and leaf (IC50 = 31.54 µgml ) possessed the most efficient antioxidant potential (free radical scavenging assay of DPPH) which was closely followed by DCM fraction of leaf with an IC  value of 33.78 µgml-1. The least antioxidant activity (albumin denaturation technique) was seen in the n-Hexane fraction of leaf and IC value was 94.74 µgml-1. The lowest anti-inflammatory potential was shown by n-Hexane fraction of both root (IC   =  71.80 µgml-1) and stem (IC   =  71.21 µgml-1) while the highest anti-inflammation was demonstrated in root by Methanol fraction with an  IC -1  value of 39.01µgml-1  closely follow in leaf by Butanol-1 fraction whose IC50 value was 39.00 µgml  , n-hexane fraction (IC50 = 39.21 µgml     ), and methanol fraction (IC50 = 39.79 µgml-1). Hence, the results indicated that leaf part showed the most prospective anti-inflammatory activity. From the present study, it may be concluded that the plant has great medicinal potential and further researches are needed to explore its potential.